As the wave of innovation and entrepreneurship deepens, the maker space has become a new platform for innovation and entrepreneurship development that gathers services, capital, technology and other resources. However, after experiencing explosive growth, most of the makerspaces were unable to create value for the settled enterprises and other relevant stakeholders due to a series of problems such as excessive dependence on the government, and finally went bankrupt. Therefore there is an urgent need to change the traditional value creation mode with a linear one-way chain, and co-create value with new start-ups and other entities through interactive cooperation and resource integration. According to the value co-creation theory, as a dynamically evolving complex network system, the maker space has the conditions to realize the value co-creation process of "value sharing (value co-creation input)-value acquisition (value co-creation result)". In this system, the multiple value-creation entities such as new ventures, government departments, investment institutions and service institutions take the maker space as the core, and share values on the basis of adhering to the concept of openness and cooperation. At the same time, these subjects continue to participate in entrepreneurial practice through internal network connection, promote efficient transmission and circulation of internal resources, so as to achieve the value co-creation of multi-agent in the maker space. Therefore, it is an urgent demand to realize this value co-creation process for the high-quality development of the maker space. #br#On the basis of the value co-creation process of "value sharing (value co-creation input) - value acquisition (value co-creation result)", this paper extracts eight input elements of participating in value sharing from three levels of the maker space, the new venture and the third-party service provider, and establishes a theoretical model of the synergistic effect of input elements on value co-creation, so as to find the path to realize the value co-creation.#br#This study takes the maker spaces in each province and region as a whole, and selects the maker spaces in 30 provinces, municipalities and autonomous regions as the research objects, except Hong Kong, Macao, Taiwan and Xizang. Given that the output of each indicator of the value co-creation result has a certain period, the antecedent condition includes the data of 2020, and the outcome variable involves the data of 2021.The study adopts the fsQCA method to explore the realization path of value co-creation driven by multi-agent input factors in the maker space.#br#It is found that there are four paths for the value co-creation of multi-agent in the maker space, which can be summarized into three types according to different core conditions, namely, the type of domination by the third-party service provider, the type that takes the service of makerspace as the main element and supported by technology, and the type of total factor aggregation. The third type is the optimal realization path, and only when the input elements of each relevant subject in the maker space are improved, forming the type of total factor agglomeration, and realizing the mutual complementarity and flexible transformation of resources, will the value co-creation be steadily realized. The input elements in the third-party service provider (policy and subsidy, financial support and technical support) are the important guarantee of value co-creation. Through the exploration of the value co-creation configuration and the non-value co-creation configuration, it is found that the non-set of value co-creation of multi-agent in the maker space is not an effective configuration of non-value co-creation, indicating that there is a causal asymmetry between value co-creation and non-value co-creation of multi-agent in the maker space.#br#Different from existing studies which focus on a single level of causality, this study adopts a holistic perspective, and emphasizes that the value co-creation of multi-agent in the makerspace is not determined by a single level of factors, but depends on the cross-level and multi-factor linkage. It is helpful to deepen the cognition of the predisposing factors and action mechanism of the value co-creation of multi-agent in the maker space. Furthermore by introducing the qualitative comparative analysis into the field of maker space, it comprehensively analyzes the collaborative innovation relationship among multiple subjects in the maker space, and clarifies the role of each subject in value co-creation.#br#