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Abstract The previous literature preliminarily tested the relationship between information technology usage and open innovation, but they did not explore the influence mechanism of information technology usage on open innovation.Therefore, the paper studied the effect of information technology usage on enterprise open innovation and explained the influence mechanism between them from the perspective of transaction cost.The study shows that information technology is an important factor that promotes enterprise open innovation.In addition, the extension analyses show the fowling conclusions.Firstly, the promotion effect of information technology usage to vertical innovation cooperation is stronger than social innovation cooperation.Secondly, the promotion effect of information technology usage on open innovation in hightech industry is higher than in lowtech industry.Finally, the promotion of regional trust degree is helpful to enhance the promotion effect of information technology usage on open innovation.The existence of difference of transaction cost in open innovation between innovation cooperation types, industries and regions is an important factor that leads to the promotion effect of information technology usage on open innovation is different between innovation cooperation types, industries and regions, which supports the influence mechanism put forward by theoretical analysis.
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