数字化如何驱动区域创新生态系统结构与机制演进？锚定该问题，构建“情景—组织—机制”框架，对中关村科技园区进行纵向案例研究。研究表明：①数字化情景以创新主体、创新资源、创新环境为触点，园区组织结构呈现“聚合化—网络化—生态化”发展态势；②数字化下园区创新生态系统的创新机制聚焦在适应、互动和共生3个维度，其中，在市场需求的适应机制上，案例样本在时间线上呈现出“被动适应—主动适应—引领适应”的变异特征；在与合作资源的互动机制上，则沿着“资源共享—知识转移—利益分配”的路径迭代；在系统主体间共生机制上，表现出“寄生共生—偏利共生—互利共生”的演进轨迹。

At present, China's regional innovation development has evolved into an innovation ecosystem model. The regional innovation ecosystem is an open system characterized by multi-subjects, multilateral relations and multi-level structure. Under the background of digitalization, the regional innovation ecosystem relies on the connectivity and aggregation characteristics of digital technology to reshape and mutate the organizational structure and innovation mechanism of the ecosystem. In turn, digitalization triggers the iteration and restructuring of innovation elements and organizational paradigms in regional innovation ecosystems, as well as the upgrading of evolutionary paths. In the existing research, there is still an obvious gap in the exploratory research and practice of regional innovation ecosystems under digitization, and thus the existing research has failed to explore the evolution of regional innovation ecosystems' structure and mechanism from the perspective of digitization.#br#In view of this, in order to clarify the evolution process of the structure and mechanism of the regional innovation ecosystem against the backdrop of digital innovation, this paper analyzes the development practice of Zhongguancun Hi-tech Industrial Development Zone for more than 30 years, and forms a triangular validation by means of in-depth interviews, participatory observation, and other first-hand and second-hand data. By coding the data at three levels, 18 first-order concepts, 9 second-order themes and 3 aggregated constructs are formed for the analysis of the evolution process of the structure and mechanism of the regional innovation ecosystem under digitalization.#br#It is found that the evolution of the digital regional innovation ecosystem is based on the specialization of innovation subjects, diversification of innovation resources and sound innovation environment as a starting point, relying on digital technology and data elements to aggregate, connect, and integrate innovation subjects and external innovation resources, and ultimately realizing the value of co-creativity of the regional innovation ecosystem, forming the characteristics of "information-based industrial aggregation—networked industrial ecology—digital regional ecology", and ultimately presenting the process of the evolution of the organizational structure of "aggregated-networked-ecological". Moreover, contexts dominate the digital change of the ecosystem collaborative innovation management model, and the regional innovation ecosystem is interpreted in terms of the three contextual dimensions of the innovation subject, innovation resources, and innovation environment. Specifically, innovation subjects rely on digital technology for role change, while innovation resources between heterogeneous subjects realize integration and synergy under the evolution of the innovation environment. Finally, the mechanism evolution path of regional innovation ecosystem under digitalization is summarized as follows: (1) the adaptation mechanism evolves according to the path of "passive adaptation—active adaptation—leading adaptation" based on the adaptation of the needs of the innovation subject; (2) the interaction mechanism makes the interaction of innovation resources evolve according to the path of "resource aggregation—knowledge transfer—value co-creating"; (3) the symbiosis mechanism evolves the innovation elements according to the path of "parasitism—biased symbiosis—mutual benefit symbiosis".#br#In summary, this paper proposes the organization and evolution mechanism of the regional innovation ecosystem under digitalization, which provides useful reference for the digital construction of the regional innovation ecosystem. The regional innovation ecosystem relies on digital technology to connect and unite industrial chain innovation subjects, and improve the competitiveness of regional industries as a whole. Thus, it realizes the complementary advantages between innovation subjects and optimizes the interaction of innovation resources. There are still certain limitations to this study. First, this paper adopts the exploratory vertical single-case study method. Limited by the number of research objects, the universality of the research conclusions needs further discussion. Multiple case studies or cross-industry studies can be conducted in the future to further test the conclusions drawn from this study. Second, the exploration of specific management mechanisms is still limited, and it is necessary to analyze the functional principles of the mechanisms through quantitative means in the future. Finally, the Zhongguancun Science and Technology Park is taken as the main support for innovation elements in this study, with a focus on the interaction and collaboration of internal innovation elements in the system. However, there are still limitations in exploring the distribution and external innovation elements in the region, which await future research.#br#